Ghayeghran played most of his club career for Malavan Anzali FC. In 1990 he signed for Al-Ittihad of Qatar and briefly played in the Qatar league before returning back to Malavan, helping the club win the Hazfi Cup and participate in the Asian Club Championship. In 1993 he moved to the big-spending team of the time Keshavarz FC, where he was also a coach.
Ghayeghran moved to second division team Masoud Hormozgan where he coached once again. In 1997 and 1998 Ghayeghran stated numerous times that he would like to be involved with Malavan again, either as a coach or player.
International career
In February 1986 he made his debut for the national team against Pakistan. In 1987 Ghayeghran became the national team captain after most of the already established national team members who had participated in the Asian tournaments from 1984 to 1986 resigned from playing (these included top stars such as Nasser Mohammadkhani, Hamid Alidoosti, Shahrokh Bayani)
In 1988 thanks to Ghayeghran's leadership an underprepared and inexperienced Iran side finished third in the Asian Cup tournament. He and Mehdi Fonoonizadeh came out as the two players with their trademark long-range shots, which usually compensated for a shortage in the area of teamwork. Two years later the team became the 1990 Asian Games champions, where Ghayeghran scored one of the most memorable goals in Iranian football history against South Korea.
He finished his international career with 40 caps and 6 goals.
Ghayeghran was involved in a car accident while driving towards Tehran during Nowrooz vacation with some family members. This resulted in the tragic death of Ghayegran and his young son.
Sirous was announced dead on April, 7th 1998.

Legacy
Ghayeghran's love of football began early, playing with local children in the streets and alleys of his home city. He was soon playing in the youth provincial team of Gilan and also joined his hometown club, Malavan. Even at a young age, Ghayeghran was known to be a down-to-earth person, with a great attitude, and instantly became a fan favorite.
Ghayeghran will always be remembered as one of the finest examples of an athlete in Iran. He helped charities privately, and always had time for his fans. He paved the way for players who were not born or raised in Tehran to make it to the national team and helped Malavan and Bandar Anzali earn a place in Iranian football.